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KMID : 1134820230520040426
Journal of the Korean Society of Food Science and Nutrition
2023 Volume.52 No. 4 p.426 ~ p.430
Analysis of the Contents of Morus alba L. and Cudrania tricuspidata Leaves and Inhibitory Effects on Adipocyte Differentiation
Choi Sang-Yoon

Yoon Gui-Jae
Hur Jin-Young
Choi In-Wook
Abstract
Morus alba L. and Cudrania tricuspidata leaves have been reported to show anti-oxidative, anti-diabetes, and anti-obesity effects. However, no study to date has carried out a comparison of the contents of these leaves and their anti-adipogenesis effects. In this study, 15 compounds (caffeic acid, p-coumaric acid, chlorogenic acid, cryptochlorogenic acid, protocatechuic acid, catechin, epicatechin, kaempferol, kaempferol 3-D-glucopyranoside, quercetin, quercitrin, isoquercitrin, resveratrol, oxyresveratrol, and umbelliferone) contained in the extracts of Morus alba L. and Cudrania tricuspidata leaves were analyzed, and their inhibitory effects on adipogenesis were examined using 3T3-L1 preadipocytes. The results showed that the contents of 10 compounds were higher in Morus alba L. leaves extracts compared to Cudrania tricuspidata with the exceptions being p-coumaric acid, quercitrin, quercetin, kaemperol, and cryptochlorogenic acid. Also, Morus alba L. leaves extract had a higher inhibitory activity on adipocyte differentiation compared to that of Cudrania tricuspidata leaves extract. These results suggest that Morus alba L. leaves would be useful as an anti-adipogenesis material.
KEYWORD
Morus alba L., Cudrania tricuspidata, leaves, adipogenesis, ingredient
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